Product name | D-Biotin / Vitamin H / Vitamin B7 / Coenzyme R |
CAS No. | 58-85-5 |
Molecular Formula | C10H16N2O3S |
Molecular Weight | 244.315 |
Quality Standard | 98% up by HPLC, USP/EP |
Appearance | White powder |
ITEM | SPECFICATION | RESULTS |
Assay | 98%-100.5% | 99.3^ |
Characters | White crystalline powder | Conforms |
Identification |
IR | Match with the reference IR spectrum | Conforms |
Specific optical rotation | +89°-+93° | +91° |
Reaction time | Be similar to the reference solution | Conforms |
Loss on drying | ≤0.4% | 0.09% |
Related substances |
Any impurity | ≤1.0% | 0.03% |
Total impurities | ≤2.0% | 0.11% |
Microbial Test |
Total Plate Count | <1000cfu/g | 245 cfu/g |
Yeast & Mold | <100cfu/g | 30 cfu/g |
Escherichia coli | Negative/g | Negative |
Staphylococcus aureus | Negative/g | Negative |
Pseudomonas aeruginosa | Negative/g | Negative |
Entericbacteria | Negative/g | Negative |
Salmonella | Negative/10g | Negative |
Conclusion | Conforms with USP40 standard |
D-Biotin, also known as vitamin H or coenzyme R, is a water-soluble B-vitamin (vitamin B7).
It is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
Function of D-Biotin
1) Vitamin B7 (D-biotin) is the essential Nutrients of the retina,the Biotin deficiency could cause the dry eyes, keratization,inflammation, even blindness.
2) Vitamin B7 D-biotin) deficiency will cause reproductive functions recession, bad bone growth and the obstruction of embryo and early childhood growth.
3)Vitamin B7 (D-biotin) is used in skin care and hair care products with the function of skin whitening and nails smooth, and it has the effect of hair care and hair growth.
