Product name | Chondroitin sulfate / CS |
CAS No. | 9007-28-7 |
Molecular Formula | H2O4S.xUnspecified |
Grade | Pharma grade, food grade |
Quality Standard | 99% up by HPLC, USP/EP |
Appearance | White powder |
COA of Chondroitin Sulfate |
TESTING ITEMS | SPECIFICATION | RESULTS |
Appearance | White or almost white powder | Almost white powder |
Identification | A)Infrared absorption: The IR spectrum is consistent with RS | Conforms |
B) Meet the requirement of Sodium | Conforms |
Clarity and color of solution | Absorbance ≤0.35 | 0.13 |
PH | 5.5~7.5 | 6.6 |
Loss on drying | ≤12.0% | 9.2% |
Residue on ignition | 20.0%~30.0% | 23.4% |
Chloride | ≤0.50% | <0.50% |
Sulfate | ≤0.24% | <0.24% |
Heavy metals | ≤0.002% | <0.002% |
Organic volatile impurities | ≤0.5% | Meets the requirements |
Electrophoretic purity | Individual impurity ≤2% | <0.2% |
Limit of protein | ≤6.0% | 3.4% |
Content (on dried basis) | 95.0%~105.0% | 97.2% |
Microbial enumeration | bacterial count. ≤1000cfu/g | 40CFU/g |
Molds and yeasts count. ≤100cfu/g | <10CUF/g |
Salmonella and Escherichia coli: Negative | Negative |
Conclusion: The Product Conforms to USP. |
Function of chondroitin sulfate
The main application route of chondroitin sulfate （CS） in medicine is as a medicine for the treatment of joint diseases. When used in conjunction with glucosamine, it has the effect of relieving pain and promoting cartilage regeneration, which can fundamentally improve joint problems.
Randomized placebo-controlled clinical trials have demonstrated that chondroitin sulfate reduces pain, improves joint function, reduces joint swelling and fluid buildup in patients with osteoarthritis, prevents narrowing of spaces in the knee and hand joints, provides cushioning, and eases movement The impact and friction of slack can draw water into the proteoglycan molecules, thicken the cartilage, and increase the amount of synovial fluid in the joints. One of the important functions of chondroitin is to act as a conduit, delivering important oxygen supply and nutrients to the joints, helping to remove wastes from the joints, and expel carbon dioxide and wastes at the same time. Since articular cartilage has no blood supply, all oxygenation, nourishment, and lubrication comes from synovial fluid.
