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HOME >> PRODUCTS >>API >> Febuxostat 144060-53-7
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Febuxostat 144060-53-7

98.5% up, EP/USP/BP
99% up by HPLC, EDMF
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  • Product Details

Product Information


Product name

Febuxostat

CAS No.

144060-53-7

Molecular Formula

C16H16N2O3S

Molecular Weight

316.3748

Quality Standard

99% up by HPLC, EDMF

Appearance

White powder


COA of Febuxostat                                                                    


ITEMS

SPECIFICATIONS

RESULTS

CHARACTERISTICS

A WHITE OR WHITE CRYSTALLINE POWDER

COMPLIES

IDENTIFICATION

POSITIVE

COMPLIES

SOLUBILITY OF SOLUTION 

AND COLOUR

COMPLIES

COMPLIES

ASSAY(BY HPLC)

98%~102%

99.7%

RELATED IMPURITIES

NMT0.1%

0.1%

LOSS ON DRYING

NMT0.5%

0.2%

RESIDUE ON IGNITION

NMT0.2%

0.05%

HEAVY METALS

NMT0.001%

NMT0.001%

CONCLUSION:THE PRODUCT COMPLIES WITH EDMF STANDARD.


Usage                                                                                          


Function of Febuxostat

The main effect of febuxostat is to promote uric acid excretion and inhibit uric acid production.


At present, the drugs for the treatment of elevated uric acid in my country mainly include two categories: 1. Drugs that promote the excretion of uric acid, such as benzbromarone; 2. Drugs that inhibit the production of uric acid, the most representative of which is allopurinol. Febuxostat is a new type of uric acid-lowering drug with a similar mechanism of action to allopurinol, mainly inhibiting xanthinase, thereby inhibiting the production of uric acid. At the same time, febuxostat has less side effects and has less impact on liver and kidney function, especially patients with moderate or lower renal insufficiency can use febuxostat with confidence. At the same time, patients can achieve a good therapeutic effect on gout by cooperating with diet and strict low-purine diet.


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+86 15860782800

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