Product name | Chlortetracycline |
CAS No. | 57-62-5 |
Molecular Formula | C22H23ClN2O8 |
Molecular Weight | 478.92 |
Quality Standard | 95% up by HPLC |
Appearance | White powder |
ITEMS | STANDARD | RESULTS |
Characters | Yellow powder | Conforms |
Identification | A | Thin-layer chromatography | Conforms |
B | As description of EP6 |
C | Reaction of chlorides |
PH | 2.3-3.3 | 2.51 |
Water | ≤2.0% | 0.45% |
Spec. Rotation | -235° - -250° | -248° |
Sulphated Ash | ≤0.5% | 0.14% |
Absorbance | 460nm ≤0.40 | 0.218 |
Related Substances | 4-Epichlortetracycline | ≤4.0% | 1.47% |
Total of other impurities | ≤1.0% | 0.78% |
Heavy Metals | ≤50ppm | < 50ppm |
TC.HCL( on dried basis) | ≤8.0% | 3.36% |
CTC.HCL(on dried basis) | ≥89.5% | 93.23% |
TC.HCl+CTC.HCl(on dried basis) | 94.5%-102.0% | 96.59% |
Function of Chlortetracycline
Chlortetracycline is a broad-spectrum antibiotic of the tetracycline class, which has a good inhibitory effect on Staphylococcus aureus, Streptococcus pyogenes, pneumococcus and Chlamydia trachomatis. At present, it is commonly used for skin infections. For example, it is often used in external dosage forms. Chlortetracycline hydrochloride ointment can be used to treat purulent skin diseases such as impetigo, mild small burns and ulcer infections. The method of use It is for topical application. During use, occasionally it may cause skin redness, rash and other allergic reactions. It should be noted that patients who are allergic to tetracycline antibiotics should be prohibited from using it. In addition, if you are pregnant, breastfeeding women, children should also avoid using it.
When taking the medicine, avoid contact with mucous membranes such as eyes, nose and mouth. In addition, if there is a burning sensation, itching, redness and swelling at the medication site, the medication should be stopped, the local medication should be washed, and if necessary, consult a doctor.
