Product name | THYMOPENTIN |
Molecular Formula | C30H49N9O9 |
Molecular Weight | 268.93 |
CAS No. | 69558-55-0 |
Quality Standard | 99% up, medical grade |
Appearance | White powder |
Sequence | Arg-Lys-Asp-Val-Tyr-NH2 |
Character | Composed of arginine, lysine, aspartic acid, tyrosine and valine amino acid |
Test Item | Specification | Results |
Appearance | White to off-white powder | Off-white powder |
Solubility | Very soluble in water, slightly soluble in ethanol, insoluble in ethyl acetate, ether and petroleum ether | Conform |
Specific rotation | -14.0o ~ -22.0o | -16.5o |
Biuret reaction | Should appear positive reaction | Positive reaction |
IR | Infrared spectrogram should conform to reference substance | Conform |
HPLC | Retention time of main peak of test sample should be consistent with reference substance | Conform |
pH | 7.0-9.0 | 8.1 |
Water | NMT 5.0% | 2.6% |
Amino acids | Arg 0.8-1.2 Asp 0.8-1.2 Lys 0.8-1.2 Tyr 0.8-1.2 Val 0.8-1.2 |
Conform |
Related substance | Single impurity NMT 1.5% Total impurity NMT 2.5% | 0.2% 0.3% |
Bacterial endotoxin | < 5EU/mg | Conform |
Assay | 97.0% - 103.0% | 101.1% |
Conclusion | It conforms to the enterprise standard |
Introduction of Thymopentin 69558-55-0:
Pharmacological effects:
Cell immunoregulatory drugs, can induce T cell differentiation and promote the development of T lymphocyte subsets, mature and activation function, and to adjust the proportion of lymphocyte subsets, it close to normal.
Indications:
Can be used to improve the radiotherapy and chemotherapy for cancer patients immunocompromised result. It can normalize and prevent all kinds of cellular immune deficiency to some extent and thus a potential immune modulating agents.
