Product name | Empagliflozin Intermediate(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran |
Synonyms | Empagliflozin int3; Empagliflozin-7; Empagliflozin Bromo Impurity; (S)-4-bromo-1-chloro-2-(4-tetrahydrofuran-3-yloxy-benzyl)-benzene; 3-[4-[(5-broMo-2-chlorophenyl)Methyl]phenoxy]tetrahydro-; (3S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydro-furan; (3S)-3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]oxolane 915095-89-5 |
CAS No. | 915095-89-5 |
Molecular Formula | C17H16BrClO2 |
Molecular Weight | 367.66 |
Molecular Structure |  |
Quality Standard | 99% up by HPLC |
Appearance | White to off-white powder |
3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran Chemical Properties |
Melting point | 49-51°C |
Boiling point | 459.1±45.0 °C(Predicted) |
density | 1.431±0.06 g/cm3 (20 ºC 760 Torr) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
(3S)-3-[4-[(5-Bromo-2-chlorophenyl)methyl]phenoxy]tetrahydrofuran is used as a reactant in the efficient synthesis of empagliflozin inhibitor of SGLT-2 utilizing AlCl3-promoted silane reduction of β-glycopyranoside.