Product name | Amikacin intermediate Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric (CBZ-L-HABA) |
Molecular Formula | C12H15NO5 |
Molecular Weight | 253.25 |
CAS No. | 40371-50-4 |
Quality Standard | 99% up by HPLC, medical grade |
Appearance | White powder |
COA of Amikacin Intermediate 40371-50-4 |
ITEMS | SPECIFICATION | RESULTS |
DESCRIPTION | WHITE OR OFF-WHITE SOLID POWDER | OFF-WHITE SOLID POWDER |
MELTING RANGE | 75.0℃-79.0℃ | 76.0℃-78.5℃ |
LOSS ON DRYING | ≤1.0% | 0.12% |
SPECIFIC ROTATION | -3.5°to -7.0° | -4.75° |
ASSAY | ≥98% | 99.15% |
RESIDUE ON IGNITION | ≤1.0% | 0.05% |
CONCLUSION | CONFORMS TO THE ENTERPRISE STANDARD |
STORAGE | AIRTIGHT, PROTECTED FROM LIGHT, IN COOL AND DRY PLACE. |
Amikacin intermediate 40371-50-4(Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric (CBZ-L-HABA)) is a key intermediate of Amikacin. Amikacin is an aminoglycoside antibiotic, a white or off-white powder or a crystalline powder; almost odorless and tasteless. Its mechanism of action is to act on ribosomes in bacteria, inhibit bacterial protein synthesis, and destroy the integrity of bacterial cell walls, causing bacterial cell membrane destruction and cell death. Suitable for infections caused by Gram-negative bacilli and penicillin-resistant Staphylococcus aureus.
