(+)-Cloprostenol Isopropyl Ester 157283-66-4

(+)-cloprostenol Isopropyl Ester is the optically active, 15(r) enantiomer of cloprostenol responsible for the majority of its biological activity. it is 200 times more potent than pgf2α in terminating pregnancy when given subcutaneously at a daily dose of 0.125 μg/kg in rats and hamsters, without the side effects associated with pgf2α. (+)-cloprostenol was also shown to be a potent inhibitor of rat adipose precursor differentiation in primary cultures with an ic50 value of 3 x 10-12 m. cloprostenol isopropyl ester is a more lipid soluble form of cloprostenol, which may be more amenable for certain formula