Product name | Dinoprost Trometamol Dinoprost Tromethamine Prostaglandin F2a tris salt |
CAS No. | 38562-01-5 |
Molecular Formula | C24H45NO8 |
Molecular Weight | 475.6 |
Quality Standard | 97% up, Medicine Grade |
Appearance | White to off-white powder |
COA of Dinoprost Tromethamine |
TEST | SPECIFICATION | RESULTS |
Appearance | White to off-white powder | Off-white powder |
Specific rotation | +19。- +26。 | +24.0。 |
Loss on drying | ≤ 1.0% | 0.16% |
Residue on ignition | ≤0.5% | 0.01% |
Identification IR | The IR spectrum of the sample exhibits maximum only at the same wavelength as that a similar preparation of USP Dinoprost Tromethamine RS |
Conform |
Related substances Impurity A Impurity C Any unspecified impurity Total impurities |
≤ 2.0% ≤ 1.5% ≤ 0.5% ≤ 2.0% |
0.76% Not detected 0.35% 0.44% |
Residual Solvents Methanol Ethanol Acetontrile Acetone Ethyl acetate Tetrahydrofuran |
≤ 3000ppm ≤ 5000ppm ≤ 410ppm ≤ 5000ppm ≤ 5000ppm ≤ 720ppm |
Not detected Not detected Not detected 621 ppm Not detected Not detected |
Assay | 95.0%-105.0% (on the dried basis) | 97.6% |
Conclusion | Complies with the USP and in-house standards |
Function of Dinoprost Tromethamine
Dinoprost Tromethamine is a synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum.
Application of Dinoprost Tromethamine
Estrus synchronization, induction of parturition; Treatment of persistent corpus luteum, induction of delivery and expulsion of stillbirth; Treatment of endometriosis.
Our Advantage of Dinoprost Tromethamine
1. Excellent quality: impurity A: NMT 0.1%, impurity B: 0%, Total impurity: NMT 1%; assay 97% up.
2. GMP, DMF available
3. Large capacity & stock : 10 kg/month with available stock for prompt shipment
